Muito cuidado com as supostas vacinas muito eficazes

Muito cuidado com as supostas vacinas muito eficazes

Peça de opinião do editor do BMJ, sobre as falácias e mentiras das vacinas salvadoras com “90% de eficácia”. Não são, nem perto, muito menos reduzem o que interessa: doença grave e infeção. Apenas manipulação bolsista.

Let’s put this in perspective. First, a relative risk reduction is being reported, not absolute risk reduction, which appears to be less than 1%. Second, these results refer to the trials’ primary endpoint of covid-19 of essentially any severity, and importantly not the vaccine’s ability to save lives, nor the ability to prevent infection, nor the efficacy in important subgroups (e.g. frail elderly). Those still remain unknown. Third, these results reflect a time point relatively soon after vaccination, and we know nothing about vaccine performance at 3, 6, or 12 months, so cannot compare these efficacy numbers against other vaccines like influenza vaccines (which are judged over a season). Fourth, children, adolescents, and immunocompromised individuals were largely excluded from the trials, so we still lack any data on these important populations.

Peter Doshi: Pfizer and Moderna’s “95% effective” vaccines—let’s be cautious and first see the full data

 

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